Two swimmers due to compete for ROC at the Tokyo 2020 Olympics have been provisionally suspended for anti-doping offences, the International Swimming Federation (FINA) has announced.
The suspensions stem from the World Anti-Doping Agency (WADA) investigation into manipulation of Moscow Anti-Doping Laboratory data.
Veronika Andrusenko - a two-time Olympian who has won medals at the World Championships - is one of the athletes provisionally suspended, having been charged with an anti-doping rule violation.
The other is Universiade 200 metres butterfly champion Aleksandr Kudashev.
"FINA is grateful to WADA for its diligence in helping to ensure clean competition at Tokyo 2020," FINA President Husain Al-Musallam said.
"As a proud signatory of the WADA Code, we have followed up quickly and carefully to process the information supplied as a result of the work of WADA’s investigations and intelligence unit.
"FINA remains fully committed to protecting clean athletes and promoting clean competition at Tokyo 2020, just as we do for all the events on our calendar."
Andrusenko won a women's 4x100m medley silver medal at the 2017 World Championships in Budapest, to go with a bronze won in the same event in Barcelona in 2013.
The 30-year-old has additionally won three silver medals at Short Course World Championships - including in the 400m freestyle at Canadian venue Windsor in 2016.
Andrusenko won a 4x200m freestyle bronze at the same event.
At Tokyo 2020, Andrusenko was entered to compete in the 200m freestyle and Kudashev was set to race in the 200m butterfly.
The pair were in a 56-strong team of ROC swimmers and could also have contested the relays - but their Olympic ambitions appear over with the announcement of the suspensions.
Russia's name, flag and anthem have been banned from the Olympics as part of a package of sanctions imposed on the country by WADA and the Court of Arbitration for Sport because of state-sponsored doping and manipulation of the Moscow Anti-Doping Laboratory data in the "cover-up of the cover-up".
"Neutral" Russian athletes are able to compete at Tokyo 2020 under the ROC banner, and the same system is due to be in place at Beijing 2022.
Russian swimmers were able to compete at Rio 2016 and won four medals.