The duo lost to world number 64 pairing Jeong Na Eun and Kim Hye Jeong of South Korea 21-15, 21-16.

"I was nervous, but we wanted to play without pressure," said Jeong after the match.

"I wasn’t aware of (Yi Fan’s injury) at first but halfway through the second set, I realised she wasn’t in good form. The aim then was just not to make any mistakes."

The 2020 champion Yuki Fukushima and Sayaka Hirota of Japan went down to Chinese pairing of Zhang Shu Xian and Zheng Yu 21-19, 11-21, 21-11 in a 90-minute encounter.

Elsewhere, India’s PV Sindhu started aggressively to beat Wang Zhi Yi of China 21-18, 21-13 in a bid to win her first All England title.

World number one Tai Tzu Ying of Chinese Taipei also progressed to the next round after beating Belgian Lianne Tan 21-12, 21-14 while world champion Akane Yamaguchi of Japan brushed past Estonian Kristin Kuuba 21-13, 21-13.

Among men, Danish super star Anders Antonsen upset world champion Loh Kean Yew of Singapore 21-15, 18-21, 21-13.

"I needed to be prepared for his speed," said Antonsen.

"My last match was against Loh, so it was fun to get another chance at beating him. I was eager to get out there and played a fine match."

Loh Kean Yew, who won the world title five months ago, said: "My luck with the draw has never been the best, so I’m used to it! He made no mistakes in the third and kept up the pressure."

India’s Sai Praneeth was no match for Olympic champion Viktor Axelsen of Denmark.

Axelsen, who beat Praneeth 22-20, 21-11, will be aiming to reclaim the title he won in 2020 after last year’s final defeat.

"It feels great to be back and to see all the fans back in the stands," said Axelsen.

"I have great memories from here now, it’s one of the biggest tournaments of the year and one of my biggest dreams coming true to win it. Hopefully I can try to do that one more time.

"There is this vibe here, this atmosphere, that is really special. There is a lot of history at this tournament and every player wants to win it really bad.”