Lyles is one of five male nominations after a series of Diamond League successes, including a 200 metres personal best of 19.65 seconds.

Isner reached the Wimbledon semi-final before losing an epic 6 hour 36min match 26-24 in the final set to Kevin Anderson of South Africa.

It marked the second longest match in Wimbledon history after his own 70-68 final set win over Frenchman Nicolas Mahut in 2010.

The duo are joined by world silver medal winning fencer Eli Dershwitz and two Paralympic stars in triathlete Mark Barr and cyclist Ryan Boyle.

Barr came from behind to capture his third consecutive gold medal in the World Series Circuit in Edmonton while Boyle captured road race gold and time trial silver at the Dutch World Cup leg in Emmen.

On the women's side, Williams is nominated after reaching her 30th Grand Slam singles final before losing to Germany's Angelique Kerber.

She faces competition from swimmer Kathleen Baker, who set a 100m backstroke world record of 58.00 on the way to three individual national titles, fencing world bronze medalist Courtney Hurley and world record-equalling shooter Kim Rhode.

The list is completed by Paratriathlete Allysa Seely who claimed a third straight World Series gold in Edmonton.

The World Championship winning women's foil fencing team of Lee Kiefer, Nzingha Prescod, Nicole Ross and Margaret Lu are among the team nominees.

They are challenged by the world bronze medal winning mixed triathlon relay and the Nations League winning women's volleyball teams.

The awards seek to recognise the "outstanding achievements of Team USA athletes from last month". 

Fans can vote online for their preferred choice on the Team USA website until August 6.

Each governing body can nominate one man, one woman and one team per sport.