Cali Condors are on track to make it four wins from four this International Swimming League (ISL) season, while Energy Standard also have a big lead at the halfway stage of their match.
Paris-based Energy Standard won nine of 20 races at the Duna Arena in Budapest to end the day on 300.5 points, well ahead of second-place Tokyo Frog Kings on 235 in match nine.
Iron have 183.5 points, Toronto Titans 155.
Sweden's Sarah Sjöström - last season's Most Valuable Player - won all four races she took part in to lead the way for Energy Standard.
The triple Olympic medallist at Rio 2016 won the women's 100 metres butterfly and 50m freestyle, and brought the Energy Standard team home to win the 4x100m medley and 4x100m freestyle relays.
Iron's Turkish star Emre Sakçi again impressed, winning the men's 50m breaststroke in 25.43 seconds - 0.14 off the European record he set earlier this month.
South African Chad Le Clos, Italy's Benedetta Pilato, Lithuanian Danas Rapšys and Evgeny Rylov of Russia also won races for the Parisian franchise.
Later in the day in match 10, the two Californian outfits dominated proceedings, with nine of the 10 leading swimmers by ranking points representing either Cali Condors or Los Angeles Current.
American Condors Caeleb Dressel and Beata Nelson continued to impress, with two solo wins apiece
Dressel won the men's 50m freestyle and 100m butterfly, Nelson the women's 200m medley and 200m backstroke.
Current swimmer Ryan Murphy, also of the United States, won both the men's 200m and 50m backstroke races.
Italy's two-time Olympic medallist Federica Pellegrini, racing for the first time this ISL season having been delayed in arriving in Hungary because she had coronavirus, came fifth in the women's 200m backstroke on a disappointing day for Aqua Centurions.
Pellegrini also contributed to fourth- and seventh-place relay finishes.
Cali Condors have 285 points after 20 of 39 races, with Current 47 behind.
London Roar are third on 212 points, with Aqua last on 142.
Racing continues tomorrow, with these the last two regular-season matches.
Energy Standard and Cali Condors are among the teams to have already reached the semi-finals.