Dominic Thiem is through to the US Open semi-finals for the first time ©Getty Images

Second seed Dominic Thiem cruised into his first US Open semi-final with a dominant three-set victory over Australia's Alex de Minaur at Flushing Meadows.

The Austrian, the highest seed left in the men's draw after Novak Djokovic was disqualified, beat De Minaur 6-1, 6-2, 6-4 on Arthur Ashe Stadium to set-up a meeting with last year's US Open runner-up and third seed Daniil Medvedev.

Thiem only needed around two hours to see off his Australian opponent and continue his pursuit of a first Grand Slam title.

All of the semi-finalists are yet to win one of the four tennis majors and there will be a first new men's Grand Slam champion for the first time since Marin Čilić triumphed at the 2014 US Open.

"I guess it's somewhere in the back of the heads of all four remaining players," said Thiem, a three-time Grand Slam finalist.

"There may not be Novak, Roger and Rafa but there is Daniil, Sascha [Zverev] and Pablo [Carrena Busta].

"They are three amazing players and every one of us deserves this first title.

Victoria Azarenka thrashed 16th seed Elise Mertens to reach her first Grand Slam semi-final since 2013 ©Getty Images
Victoria Azarenka thrashed 16th seed Elise Mertens to reach her first Grand Slam semi-final since 2013 ©Getty Images

"We will give it our all.

"Once we step on the court we will forget about the other three."

In the women's draw, unseeded Belarusian Victoria Azarenka swept aside 16th seed Elise Mertens of Belgian to reach her first Grand Slam semi-final since 2013.

Azarenka, a two-time Australian Open champion, produced a superb display in a crushing 6-1, 6-0 victory.

The 31-year-old's reward is a meeting in the last four with 23-time Grand Slam winner and favourite Serena Williams.

"I'm so excited about this amazing opportunity to play a champion, someone I respect a lot and who's my friend," said Azarenka, who has struggled in her career since her return to the sport after giving birth in 2016. 

"I hope it will be fun – it'll be fun for me."