Béryl Gastaldello and Tom Shields were influential in the meet-closing skins races as LA Current leapfrogged Cali Condors to win the International Swimming League's American derby match at College Park in Maryland.
Current trailed Condors by just 0.5 points going into the second day and the gap grew to 28.5 points ahead of the skins races - a three-round 50 metres freestyle eliminator worth up to triple points - as Condors looked destined for victory.
But a one-two finish from Shields and Chase Kalisz cut the deficit to 15.5 points before Gastaldello won all three of her skins races to close the gap further.
Michael Chadwick and Ryan Held claimed second and fourth respectively as Condors claimed the win on 495 points, while Current were pushed into second place on 489.5 points.
"The way it ended today, it’s like a fairytale really," said Current head coach David Marsh.
"These guys love doing this as a team, and we only won because of the team.
"We didn’t win as many individual events as we wanted to win.
"Several times we knew we were fighting for fourths and fifths, not first and second.
"That kind of team atmosphere is what happened."
French native Gastaldello, who won the 50m freestyle and 50m backstroke on day one, ended up with five wins courtesy of her skins victories as she contributed 51.5 points towards her team's total.
Condors' superstar Caeleb Dressel matched Gastaldello's five victories as he set an ISL meet record of 61.5 points.
He set an American record of 22.21sec to win the 50m butterfly in Maryland, before clinching victory in the 100m freestyle event.
Hali Flickinger secured 400m freestyle and 200m butterfly wins for Condor, while two-time Rio 2016 Olympic gold medallist Lilly King won the 100m breaststroke to maintain her unbeaten ISL record.
Both Current and Condors share a tie at the top of the US standings and secured their place in December's ISL Final in Las Vegas.
DC Trident finished third at the meet on 322.5 points, ahead of New York Breakers, who finished fourth on 315.0 points.