Sarah Sjöström of Sweden and South Africa's Chad Le Clos will bid to extend their overall leads in the women's and men's events respectively when they compete at the International Swimming Federation (FINA) World Cup in Doha.
Sjöström, a seven-time world champion, and four-time Olympic medallist Le Clos are among the headline names due to compete at the World Cup, which begins tomorrow and concludes on Thursday (October 5).
Action is scheduled to take place at the Hamad Aquatic Complex, which staged the World Short Course Championships in 2014.
"I was here in 2014 for the World Championships, which were very successful for me," said Sjöström, who won the gold medal in the 100 metres butterfly at last year's Olympic Games in Rio de Janeiro.
"It's my first World Cup here, it's going to be fun.
"I had a very good season - I am doing the entirety of the World Cup and it's going pretty well."
Le Clos is also hoping for a successful return to the Qatari capital and also backed the Swede to enjoy a record-breaking performance in Doha.
"Doha is a second home for me, I'm coming here since 2012," the South African said.
"I hope to improve my recent performances in Hong Kong.
"I am sure that Sarah will establish a couple of world records here."
Sjöström leads the women's standings on 353 points, with Hungarian Katinka Hosszú second on 272.
Le Clos tops the men's rankings on 234 points.
American Tom Shields is his nearest competitor as he has 147 points.
FINA executive director Cornel Marculescu said Doha would use the event to prepare for its hosting of the World Championships in 2023.
"Ouside the frame of the FINA World Championships, the World Cup is the best and most privileged opportunity to further promote our sport," he said.
"The event in Doha will be spectacular, as this city is actively preparing for the 2023 FINA World Championships here in Qatar."