The three-time world champion had been expected to be one of the headline names at the Rio 2016 Paralympics, but the London 2012 T44 100 metres silver medallist withdrew from being part of the United States’ team.

He reportedly informed U.S Paralympics of the reason behind his decision in an email, having still been able for selection, despite missing the U.S Paralympic Trials in Charlotte earlier this month.

A hamstring injury was behind his omission from the trials, but his subsequent withdrawal from the team has left the Paralympic Games shorn of one of its start names, as a head-to-head with London 2012 gold medallist Johnnie Peacock of Britain had been expected.

Browne has now appeared to draw a line under his career by tweeting “I’m retired”.

“While I was breaking world records I was homeless, I’ve been through so much over the last six years,” he said.

“Track made everything worth it.

“Every struggle, every injury, every night I slept in my car to live out my dreams and take care of my family.

“Track has been my heaven and my hell... but I look to focus on my family and myself.

“I’ve gotten so many encouraging words over the last few weeks and I want to thank everyone.”

The American is currently a double world champion, having won the 100 and 200m events at the 2015 International Paralympic Committee Athletics World Championships in Doha in world record times of 10.61 and 21.27sec respectively.

Brown suffered broken ribs and a heavy concussion when a lorry in the New Year, with the vehicle having failed to stop at a red light, ultimately colliding with his car in Florida.

He had previously harboured hopes of becoming a professional American football player until a freak accident while running in 2009 forced the eventual amputation of the lower part of his right leg.

He underwent 13 surgeries in an attempt to fix the injury before he decided to have the affected area amputated.