Chulkova boasts a gold medal from the 2012 International Cycling Union (UCI) Track Cycling World Championships in Melbourne, where she won the women’s points race.

Her 28-year-old team-mate Yakushevsky, claimed a team sprint bronze medal at the 2013 European Track Cycling Championships in Apeldoorn.

The Russian had returned from a two-year doping ban earlier that year.

Their failures were reportedly by the Russian news agency TASS, who quote a source familiar to the situation.

"A couple of days ago, we learnt that meldonium was found in Yakushevsky’s and Chulkova’s doping tests,” the source said.

“These are the only two cases in the track cycling team, all the other athletes are clean.”

Their team’s head coach Sergei Kovpanets has reportedly refused to comment on the reported cases but claimed that athletes must declare whether they are taking banned substances.

Both Chulkova and Yakushevsky competed at the UCI Track Cycling World Championships, which were held in London from March 2 to 6.

Chulkova was part of the women’s team pursuit squad which finished 12th, while Yakushevsky helped the men’s team sprint to seventh place.

Russian rider Eduard Vorganov, who rides for the UCI World Tour team Katusha, is currently serving a provisional suspension having tested positive for meldonium in January.

Numerous other Russians have failed for meldonium in recent weeks after the heart-attack drug was added to the banned list of the World Anti-Doping Agency (WADA) on January 1.

The drug hit the headlines when five-time Grand Slam champion Maria Sharapova of Russia announced she had tested positive for the substance at the Australian Open in January at a press conference on March 7.

One of the most high-profile Russian athletes to have failed a test because of meldonium use is swimmer Yuliya Efimova, a four-time world champion.

She won the 100 metres breaststroke title at last year's home World Championships in Kazan and is considered Russia's leading swimmer.

Evgeny Saleev, a 2014 World Championship silver medallist in wrestling, were among five from the global superpower to be implicated this week, along with fellow wrestler Sergey Semenov and athletics trio Gulshat Fazletdinova, Andrey Minzhulin and Olga Vovk.

Others include speed skaters Pavel Kulizhnikov, Semyon Elistratov and Ekaterina Konstantinova, as well as ice dancer Ekaterina Bobrova.

Husband and wife rugby players Alexei Mikhaltsov and Alena Mikhaltsova have been provisionally suspended, while biathlete Eduard Latypov and volleyball player Alexander Markin are further Russian cases.

Developed in Lativa, meldonium was moved from the monitored to the prohibited list by WADA due to “evidence of its use by athletes with the intention of enhancing performance”.

A total of 27 Russian sportspeople have failed drugs tests for meldonium, the country’s Sports Minister Vitaly Mutko revealed yesterday.

Ben Nichols, a WADA spokesman, had claimed that the number of worldwide meldonium cases stood at 123 on Thursday (March 24).