The agreement will see the organisations conduct both in and out of competition tests for the first time in a bid to tackle an issue that has plagued the sport for decades.

CADF, UCI and USADA will work together to organise the planning of the tests as well as collaborating on sample collection.

Any samples collected will be tested for substances on the World Anti-Doping Agency Prohibited List, including erythropoietin (EPO), one of the main methods of choice for cyclists dope.

Certain samples will also be specially analysed for substances such as synthetic testosterone, and any collected could be used as part of both USADA and the UCI’s biological passport programmes.

“The UCI is strongly committed to develop and strengthen its ties with all anti-doping organisations,” UCI President Brian Cookson said.

“This agreement with USADA for the 2015 Amgen Tour of California is a new important step forward after previous collaborations set with National Anti-Doping Organisation's from Switzerland, France, and the UK among others.

“We truly believe that an effective fight for a clean sport can only be achieved through joining forces.”

USADA chief executive Travis Tygart, a key figure in the downfall of seven-time Tour de France winner Lance Armstrong, also heralded the agreement as cycling continues to fight its way back from a turbulent past.

“Global collaboration is a vital part of the work we all do in the anti-doping movement,” he said.

“The UCI and the CADF’s willingness to work in partnership with National Anti-Doping Organisations is a strong demonstration of the current UCI leadership’s commitment to moving the sport forward from the past, and we look forward to continuing to work with them in the future for the benefit of all clean athletes.”

The move comes after a series of new anti-doping measures were announced by the UCI in response to the Cycling Independent Reform Commissions (CIRC) report and recommendations, published in March.

The Tour of California, widely regarded as one of the biggest races in America, is due to begin today and runs until May 17.

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